Alkaline Phosphatase, Fluid

Alkaline Phosphatase, Fluid

Epic Mnemonic
Sunquest Mnemonic

LAB3101
FALK

Category

Chemistry

Methodology

Colorimetric

Test Performance Schedule

Sunday - Saturday

Result Availability

Within 24 hours – STAT upon request

Container

Sterile Plastic tub

Volume

Pref. Vol.: 1.0 mL fluid
Min. Vol.:0.5 mL fluid

Collection Instructions

Document source of body fluid on label and requisition

Transportation Instructions

• If fluid is bloody, centrifuge 15 minutes
• Transfer supernatant to a plastic tube
• Refrigerate

Stability

• Room Temperature: 5 days
• Refrigerated: 5 days

Causes for Rejection

• Extreme viscosity
• Hemolysis

CPT Codes

84075

Effective/Revised

03/21/2017

Determinations of alkaline phosphatase (ALKP) are important in liver and bone disorders. Levels of ALKP are increased in both extrahepatic and intrahepatic obstructive disease and cirrhosis. Other liver abnormalities such as hepatic tumors, hepatotoxic drugs, and hepatitis cause lesser elevation in ALKP levels. Pathologic new bone growth occurs with osteoblastic metastatic (e.g. breast, prostate) tumors with bone being the most frequent extrahepatic source of ALKP. If ALKP is the only raised value within a liver function panel, it should not be assumed that it is of hepatic origin. Additional testing should be done to rule out an extrahepatic source.