Chromosome Analysis, Peripheral Blood (Standard)

Chromosome Analysis, Peripheral Blood (Standard)

Alternate Test Name

Chromosome Analysis Constitutional; Cytogenetics Constitutional; Karyotype Constitutional

Epic Mnemonic
Sunquest Mnemonic

LAB738
CHROMB

Category

Sendouts

Methodology

Tissue culture, high resolution microscopic analysis of G-banded chromosomes

Test Performance Schedule

Monday - Saturday

Result Availability

14 - 18 days after setup
STAT Final Report: 7 days. STAT Preliminary Report: 2 business days

Container

Green top (sodium heparin) tube

Volume

Pref. Vol.: 8.0 mL
Min. Vol.: 3.0 mL
Pediatric Collection Min. Vol: 2.0 mL

Collection Instructions

• Routine venipuncture
• Immediately after collection, gently invert tube 5-10 times
• Do not centrifuge
• Store at room temperature

Transportation Instructions

• Room temperature
• Do NOT freeze or expose to extreme temperatures
• If ambient temperature exceeds 80º F or is below 40º F, send in an insulated container

Stability

Room temperature: 48 hours
Refrigerated: Unacceptable
Frozen: Unacceptable

Causes for Rejection

Frozen or clotted specimens

Remarks

NOTICE: Genetic tests are often subject to limited coverage and/or prior-authorization requirements. Consult the patient’s medical insurance provider before ordering this test.

For individuals with nonsyndromic developmental delay/intellectual disability, autism spectrum disorder, or multiple anomalies not specific to a well-delineated syndrome, chromosomal microarray (Code 221; Array Comparative Genomic Hybridization (aCGH), Constitutional) offers a much higher diagnostic yield than G-banded chromosome analysis and is recommended by the American College of Medical Genetics as a first-tier genetic test.

CPT Codes

88230; 88261; 88280; 88289

Effective/Revised

8/19/2019