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Phenytoin (Dilantin)

Phenytoin (Dilantin®)

Alternate Test Name

Dilantin Level

Epic Mnemonic
Sunquest Mnemonic

LAB31

DIL

Category

Chemistry

Methodology

KIMS Assay

Test Performance Schedule

Sunday - Saturday

Result Availability

Within 24 hours

Specimen Required

Container

Gold top (SST), Red top (serum), or Green top (lithium heparin) tube
Alt: EDTA - GREEN / RED

Volume

Pref. Vol.: 1.0 mL serum or plasma
Min. Vol.:0.5 mL serum or plasma

Collection Instructions

• Recommend collection at least 2 hours after intravenous dose and at least 4 hours after intramuscular dose

 

• Routine venipuncture

• Immediately after collection, gently invert tube 5-10 times

• Clot 30 minutes

• Promptly centrifuge

• If no gel barrier is present immediately transfer serum or plasma to a plastic tube and refrigerate

• Properly centrifuged gel barrier tube does not require transfer of serum or plasma to separate tube

Transportation Instructions

Refrigerated

Stability

• Room Temperature: 4 days
• Refrigerated: 4 days

CPT Codes

80185

Effective/Revised

03/28/2017

Clinical Significance

Phenytoin has been used extensively for seizure control in patients having both grand mal epilepsy (major motor), cortical focal seizures, and temporal lobe epilepsy. Serum level monitoring of the drug is essential in order to achieve maximal seizure control while maintaining minimal blood levels

 

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