Prenatal Risk, Quadruple Marker

Prenatal Risk, Quadruple Marker

Alternate Test Name

Quad Screen (Second Trimester) Maternal, Serum

Epic Mnemonic
Sunquest Mnemonic

LAB2154
QUADT

Category

Sendouts

Methodology

Immunoenzymatic Assay

Test Performance Schedule

Monday - Friday

Result Availability

1 – 3 days

Container

Gold top (SST) tube

Volume

Pref. Vol.: 1.0 mL
Min. Vol.: 0.75 mL

Collection Instructions

Do not draw specimen after amniocentesis, as this could affect results
• Routine venipuncture
• Immediately after collection, gently invert tube 5-10 times
• Clot 30 minutes
• Centrifuge within 2 hours of collection
• Refrigerate

Transportation Instructions

Refrigerated

Stability

• Room Temperature: Unacceptable
• Refrigerated (preferred): 7 days
• Frozen: 90 days

Causes for Rejection

Gross hemolysis

Remarks

Patient Information:
• For an assessment that includes neural tube defect results, gestational age must be between 15 weeks, 0 days and 22 weeks, 6 days
• Assessments for trisomy 21 (Down syndrome) and trisomy 18 (Edwards syndrome) only are available between 14 weeks, 0 days and 22 weeks, 6 days
• Collect sample prior to amniocentesis

Obtain the following information and send with sample:
• Physician phone number
• Patient’s estimated due date (EDD)
• Method used to determine EDD
• Patient weight
• Units in lbs or kg
• Patient history of insulin dependent diabetes
• Patient race
• Number of fetuses
• Number of chorions
• IVF pregnancy
• IVF egg donor date of birth
• IVF egg or embryo freeze date
• Previous Downs T21 Trisomy pregnancy
• Previous pregnancy with neural tube defect (NTD)
• Patient or father of baby has a NTD
• Current cigarette smoking status
• Initial or repeat testing

Panel Includes:
• Alpha-Fetoprotein (AFP)
• Estriol (uE3)
• Human Chorionic Gonadotropin (Total Beta-hCG; ThCG)
• Inhibin A

CPT Codes

81511

Effective/Revised

9/19/2019

Lorum Ipsum Opsom