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Salicylate (Aspirin®)

Salicylate (Aspirin®)

Alternate Test Name

ASA

Epic Mnemonic
Sunquest Mnemonic

LAB34
SALI

Category

Chemistry

Methodology

Absorbance

Test Performance Schedule

Sunday-Saturday

Specimen Required

Container

Gold top (SST), Red top (serum), or Green top (lithium heparin) tube
Alt: EDTA - GREEN / RED

Volume

Pref. Vol.: 1.0 mL serum or plasma
Min. Vol.: 0.5 mL serum or plasma

Collection Instructions

• Routine venipuncture

• Immediately after collection, gently invert tube 5-10 times

• Clot 30 minutes

• Promptly centrifuge

• If no gel barrier is present immediately transfer serum or plasma to a plastic tube and refrigerate

• Properly centrifuged gel barrier tube does not require transfer of serum or plasma to separate tube

Transportation Instructions

Refrigerated

Stability

• Refrigerated: 5 days

CPT Codes

80179

Effective/Revised

03/29/2017

Clinical Significance

Salicylate is a common drug used in many formulations due to its analgesic and anti-inflammatory properties. Salicylate overdose can cause metabolic acidosis with a high anionic gap, gastrointestinal and central nervous system disturbances, as well as encephalopathy and renal failure.

 

Serum concentrations exceeding 60.0 mg/dL are usually lethal. Salicylate intoxication occurs often in children due to its accessibility, in chronic patients with regular need of medication, or in patients who are taking combination prescription and nonprescription dosages. Overdosage of salicylate is also associated with suicide attempts in adolescents and adults.

 

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