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Alpha-Fetoprotein (AFP), Single Marker Screen, Maternal

Alpha-Fetoprotein (AFP), Single Marker Screen, Maternal
Alternate Test Name	AFP MaternalA
Epic Mnemonic Sunquest Mnemonic	LAB692 AFPMB
Category	Sendouts
Methodology	Two-Site Immunoenzymatic (Sandwich) Assay
Test Performance Schedule	Monday - Friday
Result Availability	1 – 3 days

Specimen Required

Container	Gold top (SST) tube
Volume	Pref. Vol.: 1.0 mL Min. Vol.: 0.75 mL
Collection Instructions	Do not draw specimen after amniocentesis, as this could affect results • Routine venipuncture • Immediately after collection, gently invert tube 5-10 times • Clot 30 minutes • Centrifuge within 2 hours of collection • Refrigerate
Transportation Instructions	Refrigerated
Stability	• Refrigerated (preferred): 7 days • Frozen: 90 days
Causes for Rejection	Gross hemolysis
Remarks	Patient Information: • For an assessment that includes neural tube defect results, gestational age must be between 15 weeks, 0 days and 22 weeks, 6 days • Collect sample prior to amniocentesis Obtain the following information and send with sample: • Physician phone number • Patient’s estimated due date (EDD) • Method used to determine EDD • Patient weight • Units in lbs or kg • Patient history of insulin dependent diabetes • Patient race • Number of fetuses • Number of chorions • IVF pregnancy • IVF egg donor date of birth • IVF egg or embryo freeze date • Previous Downs T21 Trisomy pregnancy • Previous pregnancy with neural tube defect (NTD) • Patient or father of baby has a NTD • Current cigarette smoking status • Initial or repeat testing
CPT Codes	82105
Effective/Revised	10/21/2020

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